The plane blew a tire as it landed, coming to rest just off the end of Runway 22R at 1:30 p.m.
American Airlines officials said no emergency was declared prior to landing, but the Chicago Fire Department was called to the runway on an 'emergency alert' and put on stand-by.
The 185 passengers were removed from the plane by stairs and bused to the terminal where they were reassigned to alternative flights.
The FAA is investigating what happened. Officials said the National Transportation Safety Board may also investigate.
The plane was due to land at JFK at 4:10 p.m.