Readers of Travel and Leisure magazine ranked Chicago No. 1. The 2010 survey also ranks U.S. cities when it comes to friendiest people, best vacation destination and more than three dozen other categories.
In addition to pizza, other Chicago bests include the skyline and business hotels. The city came in third for museums, galleries and luxury stores.
However, Travel and Leisure magazine readers ranked Chicago 34 out of 35 cities when it comes to the weather. San Diego ranked first for the best weather.
To see the full rankings, head to www.travelandleisure.com.