For example, researchers found that those taking codeine or oxycodone were at greater risk of death after only 30 days.
That compares to patients taking hydrocodone, another opoid.
Patients who took codeine for at least three months have a 62 percent greater risk for cardiovascular problems compared to those take hydrocodone.
Researchers say there are startling disparities in safety points, and tout the need for greater caution in prescribing these medications.
