Tionda and Diamond Bradley disappeared July 6, 2001.
At the time, Tionda was 10 years old, Diamond was 3. They were last seen in their apartment complex near 35th and Cottage Grove. Relatives say they left both a note and a voicemail saying they were running errands.
Their disappearance sparked one of the largest searches in Chicago Police Department history.
"I hope they are alive, but we have to face reality. It's been 10 years. They could be deceased," said Sheliah Bradley-Smith, great aunt. "Even though it's been a long time, it's still the same pain, still the same suspicions."
According to Bradley-Smith, those suspicions are that someone close to the family may be responsible for Tionda and Diamond's disappearance. Leads in the case, however, seem to be few and far between.
Initially, there were extensive searches in the neighborhood, the woods and in abandoned buildings which didn't shed light as to what happened to the girls. But their oldest sister is holding out hope that they will return home alive.
"I would be happy. I would run to them and hug them and tell them how much I love them, 'cause I really do miss my sisters," said Rita Bradley.
The family remains hopeful that detectives will make a break in the case in the near future. In the meantime, they cherish memories of the last time they say Tionda and Diamond.
"The last thing I remember Diamond, she said to me, 'grandma, I love you,'" said Mary Bradley, grandmother.
Chicago police say the case remains active with interviews being done as recently as a few days ago. They ask anyone with information to contact them.