The school confirms that a plaque honoring Spanier was removed from its lobby Thursday.
Spanier's name has also been erased from the high school's website.
Spanier was a 1966 graduate.
Penn State's board of trustees fired Spanier on Wednesday, after 16 years in the post, in the wake of a child sex-abuse scandal involving former assistant coach Jerry Sandusky.
Former Penn St. President Graham Spanier stripped of Highland Park High School honor.
