Scientists say they may have pinpointed how heart disease can lead to diabetes. It is a finding that could lead to new treatments.
Researchers discovered that the stress of heart failure activates a protein called P53. That in turn results in inflammation in fat tissue, insulin resistance and worsening heart function.
The domino effect is outlined in the journal Cell Metabolism.
Scientists say their findings clarify the reasons why the incidence of heart failure is high among diabetic patients and why the prevalence of insulin resistance is increased in heart failure patients.