Porter County Sheriff's Police say anyone who spots a white Kouts Chevrolet Impala police car with a gold stripe shouldn't approach the vehicle but report it to Indiana State Police at (219) 696-6242.
Police say it's the only Kouts police car on the road and might have been headed for Illinois. Kouts is 50 miles southeast of Chicago.
Police say the prisoner driving the car is William Francis Blankenship III, 22, of Knox, Ind. Blankenship is 5'10,"175 pounds with black hair and brown eyes. He has a goatee with some other facial hair. He was last seen wearing blue jeans and a white/gray hoodie sweatshirt. Blankenship was handcuffed when he fled in the car, police say.
According to reports, he could be heard asking police over a radio where the key to the handcuffs was and where the car's cigarette lighter was located.
Blankenship is considered armed and dangerous and could be heading toward Knox, police say.
The Associated Press contributed to this report