Two of the three people injured in crash are expected to survive. The condition of the third person, who was the wrong-way driver, is unknown.
Police say a woman was driving the Nissan GTR north in the southbound lanes of Lake Shore Drive by the Field Museum around 2 a.m. when the GTR struck a white Toyota Corolla. The Corolla then plowed into a van with a male driver. The van's driver refused medical treatment.
Authorities had to shut down the southbound lanes of Lake Shore Drive for about an hour and a half after the crash.
No charges have been filed as police investigate.
The crash left pieces of twisted metal strewn across Lake Shore Drive and the vehicles involved barely recognizable.
Tomasz Roik's mother, Malgorzata Solek of Burbank, was in her white Toyota Corolla, headed home from work around 2 a.m. when police say she was struck by the red Nissan GTR. Solek's car then hit a van, though the driver of that vehicle was able to walk away.
After emergency crews cut Solek out of her car, she underwent surgery at Northwestern Memorial Hospital to stop internal bleeding.
"You've got to see my mom right now," siad Roik. "She could've lost her life. So it's kind of painful for me, painful for my family ... I just cannot imagine how she survived that."
The two people in the car going the wrong way were also taken to Northwestern.
Shelly Williams says her 35-year-old uncle, Todd Williams, owns the red Nissan, but he was in the passenger seat being driven by a female friend.
"He was kind of shocked about the situation and everything that happened and everything," said Williams. "He's fine. He's just concerned about the other people that were involved in the accident."
This is the fifth wrong-way crash in the Chicago area in just the past month and the third in the last week.
On Monday, four people were killed when police say a driver went the wrong way on Interstate 80. And last Friday, a driver charged with driving under the influence drove six miles in the wrong direction on the Stevenson before hitting another car on the Lake Shore Drive ramp.
Malgorzata Solek, a 56-year-old grandmother of five, is expected to survive this latest incident, but her son thinks the other driver should be charged criminally.
"For me, it's attempted murder," said Roik. "Someone who's driving the wrong way and hit another car. What should I think?"
Doctors have not said how long his mother may be hospitalized. In addition to internal bleeding, she suffered multiple leg fractures.
In three out of the four previous crashes in the past month, alcohol was suspected to have played a role. In this case, police are still investigating.