They're trying to "crack the curse" by walking from Arizona to Wrigley Field with a 5-month-old goat named Wrigley in tow.
The guys arrived in Tulsa, Oklahoma, Monday. They began their journey February 25, which is also late Cubs announcer Ron Santo's birthday.
The Curse of the Billy Goat began in 1945 after the Cubs refused to allow the owner of the Billy Goat Tavern to bring his goat inside the game. Legend has it the man then told the Cubs they would never win a World Series again.
The guys say they hope to arrive in Chicago by Memorial Day. Their walk is also helping raise money for cancer research.
"Who's to say there is or isn't a curse? But if you believe it will be broken, it will be broken," said fan PJ Fisher.
"Hopefully they'll let Wrigley in, but that's up to the Ricketts family and the Cubs organization," said fan Matt Gregory.