The iftar is the meal that breaks the day of fasting, when Muslim families and communities eat together after sunset.
The meal to be served in the State Dining Room will be the fourth iftar that Obama has hosted.
It continues the tradition of hosting iftars that began annually under President Bill Clinton and was continued by President George W. Bush.
Invited guests include elected officials, religious and grass-roots leaders in the Muslim American community and leaders of diverse faiths and members of the diplomatic corps.
During Ramadan, Muslims refrain from eating and drinking from sunrise to sunset.