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PHOTOS: Letterman interviews Oprah at Ball State

Oprah Winfrey reacts to a question from Ball State University alumnus David Letterman, right, host of CBS's "Late Show," during an interview at Ball State University in Muncie, Ind., Monday, Nov. 26, 2012. The conversation is part of the David Letterman Distinguished Professional Lecture and Workshop Series. (AP Photo/Michael Conroy) <span class=meta>(AP Photo/ Michael Conroy)</span>
November 26, 2012 4:58:06 PM PST