The crash happened on the side of Mannheim near Balmoral Avenue.
According to officials, one person was killed, and another driver was taken to the hospital in good condition. It appeared that person was being treated at Resurrection Hospital.
There were unconfirmed reports Saturday that a man in his 40s was fatally struck after pulling over on the shoulder of the southbound lanes of Manheim south of Interstate 190.
His vehicle might have broken down, and he reportedly was outside of it.
Unconfirmed reports also indicate a woman driving a PT Cruiser struck and killed that man and that she might have been under the influence of alcohol at the time of accident.
Following the crash, police had the involved cars towed away from the scene.