The father of one of the children, 28-year-old Edwin Anderson. is charged with misdemeanor domestic battery.
The children were removed from their home at 82nd and Ellis in the Chatham neighborhood.
Investigators were called to the home Tuesday night about a domestic dispute. They found three girls and a boy, ranging in age from six-months to 4-years-old. Police say two had visible bruises.
All four children were taken to hospitals as a precaution.