The derailment happened at approximately 5 a.m. Will County Office of Emergency Management crews responded to the scene in the 100-block of South Main Street.
Eyewitness News is told four train cars left the tracks. Two of them were put back on by 9:15 a.m, but it wasn't known how long it would take to restore the other two cars, said Domingo Kaller, an operations specialist with the Will County Emergency Management office.
No injuries were reported, but traffic was being affected as rail crossings along Laraway Road were blocked off at Gougar Road, Cherry Hill Road and Spencer Road, Kaller said.
It was not immediately known what the train cars were carrying. No hazardous materials response was requested.
Will County authorities said they were investigating the incident.
(The Sun-Times Media Wire contributed to this report.)