Wendolyn Warren, of Jonesboro, said she rented out her home for a week and came back to find it ransacked -- a message was written in lipstick on her mirror, and a total of 28 items were missing.
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As seen on her Ring doorbell's surveillance video, Warren said a woman was wearing her 91-year-old grandmother's coat. A man is also seen trying to block the camera while the woman loads items into a car.
"They took silverware that's priceless, that came from my grandfather and my mother," Warren said.
Warren told WSB-TV that children also stayed in her home while she was gone, and the guests left behind homework and toys.
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Airbnb said it promises to reimburse hosts in cases of guests' theft.
"We are appalled by the reported behavior and are quickly working with the host to initiate a claim through our $1 Million Host Guarantee," the company told ABC News in a statement.
ABC News has not been able to contact the couple, and police said an investigation is underway.