The victim was identified to the Lake County Coroner's Office as Alonzo Smith, of East Chicago. He was shot several times around 7:30 a.m. near Casey Street and Chicago Avenue.
Witnesses who were heading west on Chicago said they saw a silver or gray vehicle cross the westbound lanes and hit the back of a truck before careening across all lanes into a parking lot, police said.
Smith was transported to St. Catherine Hospital, where he died a short time later. His death was ruled a homicide, the coroner's office said.
Anyone with information should call Detective Luis Semidei at (219) 391-8426.
The Sun-Times Media Wire contributed to this report.