Police said the crash happened at about 2 a.m. at 115th Street and Central Avenue in Alsip. First responders were told two passing motorists pulled the driver, identified as 38-year-old Mark Winslow of Chicago, from his vehicle.
The Alsip Fire Department transported Winslow to Christ Hospital, where he died from his injuries, police said.
The Alsip Police Department and the Suburban Major Accident Reconstruction Team are investigating the crash.