The animal was spotted near Hillcrest Boulevard and N. Mayflower Avenue around 5:30 a.m., making its way along residential streets and into nearby alleys.
At least one vehicle came close to the bear in the middle of a street, driving past it in the early-morning darkness.
The bear could be seen making its way into the front yards of several homes.
Just after 9 a.m., authorities tranquilized the bear and hoisted it into the flatbed of a pickup truck to be transported.
Bear seen wandering in Monrovia residential neighborhood
It was unclear whether the bear was the same animal reported in the same neighborhood on Thursday.