Monday morning, "Good Morning America" is kicking off the celebration by highlighting some of the organizations across the country making a big difference.
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RELATED: Betty White shares her secret to happiness ahead of turning 100 years young
White spoke about her love of animals on GMA in 2011. "My mother and dad were the same way. And my mother used to tell a story that if, when she brought me home from the hospital, if our cat, Toby, hadn't liked me, I would have been sent right back to the hospital."
The Hallmark Channel is also celebrating Betty White by playing a marathon of 40 straight episodes of "The Golden Girls."
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On the big screen -- select theaters across the country are showing "Betty White: A celebration" -- for one night only.
VIDEO: Betty White remembered as beloved actress and animal advocate
Bay Area remembers Betty White, actress and animal advocate