The crash happened in the 5300 block of South DuSable Lake Shore Drive near Hyde Park, Chicago police said. A 31-year-old man was driving at the location when he lost control of his vehicle and hit multiple objects.
The girl who was killed in the crash was 3 years old, police said. She was pronounced at Comer Children's Hospital.
A 9-month-old infant girl, a 9-year-old girl and a 25-year-old woman were hospitalized after the crash car, police said. They all had non-life-threatening injuries.
The infant was treated at Comer Children's Hospital. The 9-year-old girl was taken to Lurie Children's Hospital. The woman was taken to the University of Chicago Hospital.
No further information about the crash was immediately available.