The incident occurred in the 7900-block of South East End Avenue at about 8:45 p.m.
Police said the woman was crossing the street when the driver of a silver sedan hit her and left the scene.
Police believe the driver drove away westbound down 79th Street.
The woman was transported to the University of Chicago Medical Center in critical condition, police said.
Police describe the vehicle as a light color, possibly gray, 2013 - 2016 Chevrolet Malibu with Illinois plates. The car is believed to have right side front end, hood, and windshield damage.
Car is missing a right side mirror and has a long, dark mark on the driver's side door.
No one is in custody and the Major Accidents Unit is investigating.
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