According to police, someone driving a white Mercedes tried to drive away from a traffic stop near Michigan Avenue and Ohio Street around 8:45 p.m.
The driver then struck a parked car, colliding with a building and later struck the pedestrian, police said.
Police said the people who were in car the then ran from the scene.
The 38-year-old male sustained injuries to his leg and was taken to Northwestern Memorial Hospital in good condition, according to police.
No one is in custody.