Police said the first shooting occurred in the 4000-block of North Kimball just after 1 a.m., the second in the 4300-block of North Troy at 2:52 a.m., and the third in the 4800-block of North Kimball at 4:19 a.m. on November 4.
Police describe the suspects as two men wearing masks and dark clothing, driving a newer model dark gray four-door Acura with a moon roof and tinted windows.
In two of the shootings, people were seriously injured by gunfire, police said.
If you have any information contact Area North detectives at 312-744-8261.