According to police, at around 3:15 a.m. officers were travelling westbound on King Drive in a marked squad car when they collided with a Volkswagen sedan near 35th Street.
The Chicago Fire Department said a female officer, 58, and a male officer 56, were taken to University of Chicago Hospital. The male driver of the sedan was also taken to U of C in fair condition, CFD said.
Both officers are listed in fair condition, according to CPD.
It's not yet clear what caused the crash.
No further information is available at this time.