The shooting took place in the 7400-block of South Kingston Avenue at about 11:24 p.m. Police said two suspects entered the apartment and shot the victims.
An 18-year-old man was shot in the jaw and arm and a 17-year-old boy was shot in the head and cheek. Both were transported to the University of Chicago medical Center in critical condition.
A rifle was recovered from the scene and no one is in custody, police said.
Area One detectives are investigating the circumstances surrounding the shooting.
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