The shooting occurred at about 8:34 p.m. inside a home in the 100-block of North Parkside Avenue.
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Police said the teen got into a physical altercation with a 33-year-old man who produced a handgun and fired shots at the victim.
The teen was shot multiple times and was pronounced dead on the scene, police said.
A witness told police the 33-year-old man fled the scene before police arrived.
The Cook County Medical Examiner's Office identified the boy as Leontaye Taylor. He lived in the same block where the shooting occurred.
Chicago police said Sunday night that a suspect was taken into custody shortly after the incident, and charges are pending.
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Area Four detectives are investigating.
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