Union workers at the CSL Behring plant in Bradley are expected to rally at about 7 a.m.
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More than 700 workers walked off the job at 11 p.m. Wednesday.
CSL Behring is a global pharmaceutical company. They manufacture, in part, medications for bleeding disorders and immune deficiencies.
The plant in Bradley is the second largest employer in Kankakee County with a total workforce of 1,500.
Union members said the key point of deep concern regards the outsourcing of jobs from CSL union workers to third party contractors.
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The president of Local 498C said this is about job security.
The timing of the strike marks the official end of a three-year contact.
Meanwhile CSL Behring company officials said they offered workers pay hikes and other competitive benefits.