Two cars were going south on the Dan Ryan Expressway at about 12:23 a.m. after they crashed near 75th Street, the fire department said.
Two people were transported to hospitals in serious-to-critical condition, three in fair-to-serious condition and two in good condition, the fire department said.
Three children were transported to Comer Hospital and are expected to be ok. Another child was transported with the child's mother to Christ Hospital but was not injured.
One man was ejected from one of the cars and landed on the other's windshield. He's in serious condition at Christ Hospital.