Des Plaines police said they were notified of a crash at about 9:44 p.m. at the intersection of Golf and Rand roads.
Part of that intersection had to be shut down while paramedics worked on the victims.
A 60-year-old man was pronounced dead, the Cook County Medical Examiner's Office said.
Details on how many people were injured and their conditions were not immediately available.
Anyone who witnessed the crash is asked to contact Des Plaines police at 847-391-5400.