Police said the crash happened in the 1900-block of Hartrey around 11:45 a.m.
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Police did not say what led to the pedestrian being struck, but did say an adult male was taken to a local hospital in critical condition.
The driver stayed at the scene was taken into custody, police said. No one else is being sought.
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Police did not say whether or not the driver would be charged or cited, or with what.
Hartrey was closed between Emerson and Foster for a time after the crash.