Video shows the semi-truck swerving and driving erratically on the Eisenhower Expressway before it strikes a bridge support.
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The incident occurred around 11 a.m. on I-290 near Harlem Avenue, according to Illinois State Police.
FULL VIDEO: Video shows semi-truck driving erratically before crash on I-290
Semi-truck caught on video driving erratically before crash on I-290
The driver was transported to a local area hospital with unknown injuries, ISP said.
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Several westbound lanes are closed as police continue to investigate the crash.
No other information has been released at this time.