The pair entered the store in the 9600-block of Milwaukee Avenue around 7:30 a.m. Police said they took over-the-counter medication from a shelf and hid them in bags they brought with them.
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When they tried to leave the store, an employee approached and told them to put the merchandise down. Police said that's when the man pulled out a hypodermic needle, pointed it at the worker and said, "You don't want what I have."
The pair left the store and got into a light-colored vehicle. Police said they got away with about $600 in over-the-counter meds.
The man was about 5 ft. 5 in. - 5 ft. 9 in. tall, weighed around 155-175 pounds and had dark hair. He was wearing sunglasses, a dark jacket and dark pants.
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The woman was about 5 ft. 5 in. - 5 ft. 9 in. tall, weighed around 135-145 pounds and had light hair. She was wearing a baseball cap, a two-tone jacket and tan pants.
An investigation is underway. No one is in custody.
A similar robbery occurred in southwest suburban Naperville earlier this week, where a robber claimed to have a needle infected with HIV.