According to Illinois State Police, it happened about 2:20 a.m. on the outbound lanes at East Avenue in Oak Park.
The individual suffered non-life threatening injuries, police said.
All lanes reopened about 5:10 a.m., but earlier the Ike was shut down for about three hours from Austin Avenue to Harlem Avenue for the investigation.
No one is in custody.
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This is the 190th expressway shooting so far this year.
A woman was shot Friday night on Interstate 94 near Chatham on the South Side of Chicago, according to preliminary information from Illinois State police.
About 11:55 p.m., Illinois State police responded to calls of a shooting on the Dan Ryan near 83rd Street, state police said.
An investigation found that a 23-year-old woman was driving a vehicle when she was shot, state police said. She was taken to the hospital with non-life threatening injuries.
Sun-Times Media contributed to this report.