The crash occurred at about 2:52 a.m. in the northbound lanes of I-94 at Tower Road in Glencoe.
Police said the crash involved a red Pontiac, Black Hyundai, white Jeep and a gray Tesla.
At least one female passenger was transported to the hospital with injuries.
LIVE TRAFFIC: Check out the latest conditions on our live traffic map
The crash has resulted in several lane closures. As of 9:08 a.m., all lanes were back open.
Further details on the crash were not immediately available.