"I will be home, itching and missing everyone. And I can't believe it, because this film means so much to me... but such is life," said Jolie, who directed the film.
Jolie will miss the film's Monday night Los Angeles premiere, but her husband Brad Pitt and their children will attend to represent her.
The film follows the true story of Louis Zamperini, an Olympic runner who was sent to a Japanese prisoner-of-war camp.
Recently, the actress fell under the spotlight after a hacking scandal at Sony revealed producer Scott Rudin sent emails to Sony Pictures Entertainment co-chairman Amy Pascal, calling Jolie a "spoiled brat." Rudin later apologized for the remarks.