The Arlington Heights Fire Department arrived around 10 a.m. to the 1100 block of North Dryden Avenue for a detached single-car garage that was engulfed in fire, officials said.
The fire was knocked out before it could spread to the house.
Before they arrived, a man escaped the home. However, the woman couldn't get out since she uses a wheelchair.
A neighbor busted down the door to the home with a sledgehammer and carried the woman out ABC7 was told.
The couple got checked out at the scene. One of them was taken to a hospital for additional treatment, officials said.
No further information about the fire was immediately available.