The crash happened at about 5:29 a.m. in the westbound lanes near Torrence Avenue, police said.
Police confirmed that one person died. ISP said initial reports indicate the person killed was struck while changing a tire.
The investigation caused a major traffic backup into the Indiana state line.
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Police ask anyone who might have dashcam video to contact them at (847) 294-4400 or email at ISP.CrimeTips@Illinois.gov.
No other information was available.
This is a developing story; check back for updates.