The crash happened just before 4 a.m. on Tuesday morning in the west suburbs.
A stalled Ford was in the center lane and was struck by a semi, according to Illinois State Police.
A second semi then struck the first semi and rolled over on its side.
Chopper 7 was over the scene, it appeared that the semi detached from the trailer, leaving debris across the ramp.
Officials said the ramp could be closed until 7 a.m. if not longer.
ISP said there were minor injuries related to the crash.