The crash happened around 5:43 p.m. in the 6200-block North Talman Avenue in West Ridge, Chicago police said.
A 72-year-old driver in a minivan struck a pedestrian, a 4-year-old girl, who was crossing the street, police said.
The girl was taken to a hospital where she later died. She has been identified to the Cook County Medical Examiner's Office as Juslene Akeza.
The driver was cited for due care to avoid a pedestrian and failure to reduce speed, CPD said.
No further information was immediately available as Chicago police continue to investigate.