Troopers responded to the report of a shooting in the northbound lanes of the expressway near 111th Street at about 10:07 p.m., police said.
Police said a crash occurred between two vehicles, with both vehicles pulling over.
A suspect from one vehicle then fired at the victim from another vehicle, police said.
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The victim was transported to a hospital and the suspect fled the scene, police said.
Police blocked all lanes of the expressway at 119th Street as they investigate. They were back open shortly before 8 a.m.
Further details were not immediately available.
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