Cornelius Sanders was last seen on Sunday in the area of the 5100-block of South Western Avenue in the Gage Park neighborhood.
He is between 5 feet and 5-foot-3 and weighs between 100 and 115 pounds. He has brown eyes and black hair.
He may be with Cornell Sanders, a 35-year-old man.
Area One detectives asked anyone with information to call them at 312-747-8380 or dial 911.