Police said the victims were standing in a parking area in the 3500 blk. of North Belmont Harbor Drive when someone fired shots from a dark-colored SUV.
A 22-year-old man was shot in the head and pronounced dead on the scene, police said. He's been identified as Adher Luna of Cicero.
Another 22-year-old man was transported to Illinois Masonic Hospital in critical condition with a gunshot wound to his arm and chest, police said.
There is no one in custody.
Area Three Detectives are investigating.