The shooting happened around in the 2500 block of West 61st Street, Chicago police said.
The victim, a 2-year-old girl, was inside an apartment at the location when she was shot in the right leg by an unknown offender, police said.
The girl is expected to survive after being taken to Comer Children's Hospital in good condition.
Investigators would not detail if there is a possible relationship between the alleged shooter and the girl, or if they're actively searching for a suspect.
ABC7 spoke to community activist Pastor Donovan Price, who responded to the hospital where the girl's family had gathered.
"When there's a gun in the house with children... we want our children to be in school as oppose the hospital... terrible things like this don't happen," Price said.
A firearm was recovered at the scene, officials said.
Area One detectives continue to investigate.