The shooting took place in a home in the 4700-block of South Princeton Avenue at about 1:10 a.m.
Police said there was a verbal altercation and then two male suspects took out guns and shot the three victims before fleeing the scene.
A 45-year-old man was shot in the leg and transported to the University of Chicago Medical Center, where he was pronounced dead, police said. Authorities have not released his identity.
A 37-year-old man was shot multiple times and transported to Stroger Hospital, where police said he is in critical condition.
A 60-year-old man was shot in the arm and transported to the University of Chicago Medical Center in good condition.
No one is in custody and Area One detectives are investigating.
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