The shooting took place at about 1:59 a.m. in the 5500-block of South Ada Street.
Police said the victims were standing in an alley when shots were fired.
A 23-year-old man was shot multiple times and transported to the University of Chicago Medical Center in critical condition, police said.
A 23-year-old woman and 26-year-old man each walked into St. Bernard's Hospital with a wounds to the legs and are in good condition, police said.
No one is in custody and Area One detectives are investigating.
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