The shooting happened around 5:40 p.m. in the 8000 block of South Eberhart Avenue in Chatham, Chicago police said.
The victim, a 53-year-old man, was shot multiple times while he was inside residence, police said.
The man was taken to a hospital in critical condition, and he was later pronounced dead, CPD said.
His identity has not yet been released.
SEE ALSO | Woman found shot to death in West Rogers Park home, Chicago police say
Chicago police continue to investigate the death as a homicide.
No further information was available.