The shooting happened at about 4 a.m. in the 5100-block of N. Sheridan Road in the Uptown neighborhood near Edgewater, Chicago police said.
Officers responded to a call of a person shot in the area and found a 23-year-old man outside.
The victim had a gunshot wound to the head; police said he died at the scene.
SEE ALSO | Man found shot to death inside Greater Grand Crossing home, Chicago police say
A witness told police they saw a vehicle fleeing from the scene of the shooting.
Nobody is in custody. Chicago police are investigating.
INTERACTIVE SAFETY TRACKER Track crime and safety in your neighborhood