The shooting happened on Saturday at about 4:52 a.m. in the 8200 block of S. Houston Avenue, police said.
When officers arrived, they found four shooting victims.
A 20-year-old man has been shot in the neck. He was taken to U of C hospital where he died.
A 25-year-old man was shot in the abdomen; he was taken to the hospital in serious condition.
A 38-year-old man was also shot in the abdomen; he was also taken to the hospital in serious condition.
A 22-year-old woman was shot in the right arm. She is expected to be OK.
Nobody is in custody.
Police are investigating what led to the deadly shooting.
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