The shooting happened on Thursday at about 3:40 a.m. in the 1300-block of S. Ruble Street near the Dan Ryan Expressway, police said.
Chicago police said a woman, 40, was found unresponsive a gunshot wound to the head.
The Chicago Fire Department took her to Stroger Hospital in critical condition.
ABC7's cameras were at the scene, which appeared to be a homeless encampment.
No one is in custody at this time. Area Three Detectives are investigating.
No other information was available.
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