The crash happened on the southbound lanes of the Stevenson Expressway near Halsted Street in the Bridgeport neighborhood.
Illinois State Police said the crash happened at about 3:45 a.m.
Three vehicles were involved in the crash. I-55 southbound lanes were closed for about one hour. All lanes reopened by 5 a.m.
Video shows a dark-colored sedan and a Honda minivan being towed at the scene.
ISP said there were injuries, but did not say to what extent.
ISP did not say if anyone was taken into custody.
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